Grimolizzi, Franco; Arranz, Lorena (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-28)
Succinate is an essential intermediate of the tricarboxylic acid cycle
that exerts pleiotropic roles beyond metabolism in both physiological and pathological conditions. Recent evidence obtained in mouse
models shows its essential role regulating blood cell function through various mechanisms that include pseudohypoxia responses by hypoxiainducible factor-1α activation, post-translational modifications ...